On Going Research

Role of Maternal age in Microvascular Function 

This study is trying to understand the maternal age affects blood vessel function during pregnancy. Studying how people with an older maternal age are at higher risk for gestational hypertension, preeclampsia, and preterm birth. Viewing ow insufficient vascular changes may contribute to adverse effects of pregnancy.

Currently for this study we are recruiting females who are less than 27 weeks pregnant that are between the ages of 18-30 years old or greater than 35 years old. For more information reach out to ruda-lee@uiowa.edu . 

Role of ET -1, physical activity, and sedentary behavior in microvascular dysfunction following GDM

This study is to understand how the history of gestational diabetes may cause harmful changes to blood vessel function that could last a lifetime and what specifically cause those changes. Comparing people with gestational diabetes versus uncomplicated pregnancies. 

Currently for this study we are recruiting females that within the past 5 years have had a history of gestational diabetes or had an uncomplicated pregnancy. For more information reach out to grace-maurer@uiowa.edu .

Role of Inflammation in Vascular Phenotype Associated with E-cigarette Use

This study is looking at the difference in blood vessel function between E-Cigarette users and no e-cigarette use in ages between the ages of 18-24 years old. Specifically monitoring the influences on the type and activity of inflammatory cells in the blood. This could see how vaping could lead to long lasting cardiovascular affects.

Currently we are recruiting both males and females between the ages of 18-24 years old who have a history of e-cigarette use lasting at least 6 months or no history of e-cigarette use. For more information contact claire-goebel@uiowa.edu .

CAPNOVA 

This study is looking at the molecule nitric oxide and how it affects males versus females. Using local heating and dilatation substances to see the differences between the sexes. 

Currently we are recruiting males between the ages of 18-30 years old. For more information reach out to claire-goebel@uiowa.edu .

Sex Differences in the Vascular Effects of E-cigarette Use

This study is looking at the difference in blood vessel function between E-Cigarette users and no e-cigarette use in ages between the ages of 18-24 years old. Specifically monitoring the differences between genders and blood vessel function. This could see how vaping could lead to long lasting cardiovascular affects.

Currently for this study we are looking for both vaping males and females that has lasted longer than 6 months and non-vaping males. .For more information reach out to claire-goebel@uiowa.edu .

Aspirin for the Treatment of Vascular Dysfunction After Preeclampsia 

For this study we are looking at the effects of preeclampsia on blood vessel function that could have long lasting effects. Comparing a low dose of aspirin compared to a placebo in women who have had preeclampsia in the past. 

Currently we are recruiting people who a history of preeclampsia within the last five years, For more information reach out to ruda-lee@uiowa.edu . 

Metformin for the Treatment of Microvascular Dysfunction After Gestation Diabetes 

For this study we are looking at how gestational diabetes affects blood vessel function that could last a lifetime. This study is looking how a treatment for type 2 diabetes affects versus a placebo in women who had gestational diabetes. 

Currently we are recruiting females who have had a history of gestational diabetes within the last five years. For more information feel free to contact claire-goebel@uiowa.edu . 

Role of NADPH Oxidase in Microvascular Dysfunction Following GDM 

For this study we are looking at how gestational diabetes affects the blood vessel function and how it can control the blood flow. This study looks at the difference between pregnancies with gestational diabetes and uncomplicated pregnancies. 

For this study we are recruiting females who within the past five years with a pregnancy that have either had a history of gestational diabetes or an uncomplicated pregnancy. For more information reach out to grace-maurer@uiowa.edu . 

Prenatal Aspirin and Postpartum Vascular Function 

This study looks at how preeclampsia affects the blood vessel function and how aspirin in pregnancy changes the effects. Looking at the harmful effect of preeclampsia in cardiovascular disease. The comparison is between the use of aspirin and no aspirin with or without a preeclamptic pregnancy. 

We are currently recruiting females who have had a preeclamptic pregnancy within the last five years. For more information reach out to ruda-lee@uiowa.edu .