Interested in Participating in Our Research Studies?

The Microvascular Physiology Lab relies on research volunteers who participate in our studies. 

Ongoing Research Studies

Role of Inflammation and Angiotensin II In Microvascular Dysfunction Following Preeclampsia 

Women who develop preeclampsia during pregnancy are more likely to develop cardiovascular disease later in life, even if they are otherwise healthy. The reason why this occurs is unclear but may be related to blood vessel damage and increased inflammation that occurs during the preeclamptic pregnancy and persists postpartum. This study explores whether short-term treatment with an anti-inflammatory agent improves vascular function in women who have had preeclampsia. 

Women who had preeclampsia and women who did not have preeclampsia are eligible to participate in this study. We are looking for women who were pregnant within the past 2 years. For more information please contact Dr. Anna Stanhewicz: anna-stanhewicz@uiowa.edu, (319)467-1732

https://clinicaltrials.gov/ct2/show/NCT03482440?term=NCT03482440&draw=2&rank=1

Angiotensin II Receptor Inhibition to Improve Microvascular Function in Women who have had Preeclampsia

The purpose of this study is to determine the mechanisms contributing to blood vessel damage and chronic inflammation, and to test whether taking a medication that blocks angiotensin II receptors (losartan) decreases these negative effects in women who have had preeclampsia. Identification of these mechanisms and treatment strategies may lead to better clinical management of cardiovascular disease risk in these women.

Women who had preeclampsia and were pregnant within the past 2 years are eligible to participate in this study. For more information please contact Dr. Anna Stanhewicz: anna-stanhewicz@uiowa.edu, (319)467-1732

https://clinicaltrials.uihealthcare.org/studies/angiotensin-ii-receptor-inhibition-improve-microvascular-function-women-who-have-had